Universtiy of Miami Miller School of Medicine Graduate Studies

Course Descriptions

MBS 600 – Journal Club

To develop insights into the practice of biomedical research and medical practice, MBS students will be required to attend one research seminar, journal club or grand round of their choice per week. Students will prepare a written summary of the main points discussed in each event attended, and these will be monitored by their faculty advisor.

MBS 601 – Biochemistry for the Biosciences

MBS 601 covers Biochemistry in three parts. In Part 1, you will examine the biochemical composition and structure of the four basic types of biological macromolecules: carbohydrates, nucleic acids, proteins, and lipids. This part also introduces enzymes, and the composition and function of dietary nutrients and vitamins. In Part 2, you will study how genetic information flows from its storage as DNA sequence to its expression as functional RNA and protein molecules. In Part 3, you will learn how metabolic pathways are used to convert food molecules into energy and chemical intermediates used for biosynthesis of our own cellular materials.

MBS 602 – Molecular Biology for the Biosciences

To introduce students to the molecular basis of life, this course is organized around the “mother of all biological questions” – How does life arise from stochastic associations between molecules acting in networks? While the course is organized around origins of life, it actually presents the basic properties of living things, the composition and properties of biomolecules, and how each individual property arises through diffusion, mass action and affinity.

MBS 603 – Gross Anatomy & Histology

Designed to cover topics such as gross anatomy, histology, embryology, and neuroanatomy.

MBS 604 – Advanced Molecular and Cell Biology

Structure, function, biogenesis of cellular organelles, and the cytoskeleton including its regulation and dynamic interactions are discussed.

MBS 605 – Cell Physiology

General principles of cell physiology, chemical and physical structure of membranes, membrane transport and electrical phenomena, action potentials, muscle contraction, energy transduction, nerve impulse conduction and synaptic transmission.

MBS 606 – Human Neurophysiology

Physiology of the human nervous system. Physiology of vision, taste, and smell. Mechanoreceptors, nociception and pain. Spinal reflexes, hypothalamus, and autonomic nervous system. Prerequisite: MBS 605.

MBS 607 – Human Cardiovascular Physiology

Physiology of the human cardiovascular systems. Heart as a mechanical pump, electrical activity of the heart, vascular system, regulation of blood pressure and response to stress. Prerequisite: MBS 605.

MBS 608 – Basic Pathobiology

This course will cover essential nomenclature, causes of disease, cell injury and adaption, tissue regeneration and repair, and neoplasia. The pathogenesis of diseases in major organs will be presented.

MBS 611 – Mechanisms of Drug Action

Mechanisms underlying the therapeutical and pharmacodynamic properties of pharmacological agents. Emphasis is placed on cellular and molecular aspects and the quantitative factors governing equilibration within multicompartment systems and drug control of nervous and muscular function in relation to therapeutic action.

MBS 612 – Structural Biology & Drug Design

This course provides an introduction to structural biology, and illustrates how understanding the relationship between structure and function of biological macromolecules drives drug discovery.

MBS 613 – Biostatistics for the Biosciences

This course introduces students to the fundamentals of statistics from a biomedical perspective, with an emphasis on the practical application of statistical tools and the R software package for analysis and interpretation of biological datasets.

MBS 614 – Bioinformatics for the Biosciences

This course introduces graduate students to basic bioinformatics data retrieval and analysis as relevant to biomedical research.

MBS 631 – Laboratory Research or Physician Shadowing

This course will consist of rotations (minimum 2-3 hours per week for each credit hour) in selected laboratories or shadowing with UMMSM physicians. Students will be rigorously monitored for progress by faculty advisors, and present their work at a rotation symposium at the end of the semester.

MBS 680 – Professional Development Workshop

Survival Skills, Responsible Conduct of Research (RCR), Learning Skills, Lab & Animal Safety, Collaborative Institutional Training Initiative (CITI), Ethics