University of Miami >> Miller School of Medicine >> Office of Graduate Studies >> Faculty Research >> Molecular Medicine

Molecular Medicine
Faculty MemberContact
Julio C. Barredo, M.D. Julio C. Barredo, M.D.
Director, Pediatric Hematology-Oncology
Research Summary
Toppel Family Professor of Pediatric Hematology-Oncology Pediatric Oncology, Bone arrow and stem cell transplantation, Childhood brain and spinal tumors, Pediatric sickle cell disease.
 
305-585-5635 (ph)
305-325-8387 (fax)
 
Antoni  Barrientos, Ph.D. Antoni Barrientos, Ph.D.
Associate Professor of Neurology and Biochemistry & Molecular Biology
Research Summary
We are interested in the basic processes underlying the biogenesis of the mitochondrial respiratory chain (MRC) and how they bear on human neuromuscular and neurodegenerative disorders.
 
(305) 243-8683 (ph)
Rosenstiel Medical Science Building - 2067
email 
Sanjoy  Bhattacharya, Ph.D. Sanjoy Bhattacharya, Ph.D.
Associate Professor, Ophthalmology
Research Summary
Neuroproteomics, posttranslational modification of deimination, local protein synthesis in neuronal dendrites
 
(305) 482-4103 (ph)
McKnight Vision Research Center - 7th Floor
email 
Antonio  Bianco, M.D., Ph.D. Antonio Bianco, M.D., Ph.D.
Professor and Chief, Division of Endocrinology, Diabetes and Metabolism, Department of Medicine
Research Summary
Thyroid hormone action starts and ends by deiodination
 
305-243-5631 (ph)
305-243-7268 (fax)
email 
Peter  Buchwald, Ph.D. Peter Buchwald, Ph.D.
Assistant Professor Molecular and Cellular Pharmacology & Director, Drug Discovery
Research Summary
"Computer-aided drug design, small molecule modulators of the costimulatory protein-protein interaction, immunomodulation for islet transplantation"
 
305-243-9657 (ph)
Diabetes Research Institute #3014
email 
Nirupa  Chaudhari, Ph.D. Nirupa Chaudhari, Ph.D.
Professor, Physiology and Biophysics
Research Summary
We study mechanisms of transduction and cellular communication in sensory and other cells. We develop transgenic mouse models and fluorescent reporters to visualize cell function in real time. We also analyze patterns of gene expression in complex tissues to understand the roles and differentiation of diverse cell types.
 
305-243-3427 (ph)
305-243-5931 (fax)
Rosenstiel Medical Science Building - 4062
email 
Zhibin  Chen, M.D., Ph.D. Zhibin Chen, M.D., Ph.D.
Assistant Professor of Microbiology and Immunology
Research Summary
Our lab is oriented to discovery-based research on mechanisms of immune tolerance in autoimmune diseases and transplantations, as well as tumor-induced immune suppression. With advanced molecular biology tools, we strive to bridge genomic and genetic advances to immunobiology and immunotherapies in autoimmunity, transplantation and antitumor Immunity. Our current focus is on the quantitative interactions among various immune regulatory elements including CTLA4, Treg cells, and IDO.
 
305-243-8348 (ph)
305-243-4623 (fax)
Room 3035 (office), 3039A (lab) Rosenstiel Medical Sciences Building
email 
Gregory E. Conner, Ph.D. Gregory E. Conner, Ph.D.
Associate Professor of Cell Biology and Medicine; and Director of Research, Div. of Pulmonary and Critical Medicine
Research Summary
"Research projects are focused on basic epithelial cell biology especially as it applies to the respiratory tract. Projects include studies on epithelial host defense responses, secretion, ciliary beating and reactive oxygen species metabolism."
 
305-243-6926 (ph)
Rosenstiel Medical Science Building - 7061B
email 
Ram H. Datar, M. Phil, Ph. D. Ram H. Datar, M. Phil, Ph. D.
Co-Director, Biomedical Nanotechnology Institute of University of Miami (Bio NIUM), Associate Prof., Pathology
Research Summary

Molecular diagnosis and Prognosis of Cancer

Nanosensors and microfabricated devices for clinical applications

Gene expression profiling

 

305-243-6121/305-243 (ph)
305-243-6170 (fax)
Biomedical Research Building 714
email 
Sylvia  Daunert, PhD, Pharm D Sylvia Daunert, PhD, Pharm D
Professor and Lucille P. Markey Chair
Research Summary
Biomolecules and bionanotechnology
 
 
305-243-4005 (ph)
305-243-3955 (fax)
R. Bunn Gautier Building, Room 239DA (Locator R-629)
email 
Sapna  Deo, PhD Sapna Deo, PhD
Associate Professor and Biochemistry & Molecular Bilogy Graduate Program Director
Research Summary
Biomolecules and bionanotechnology
 
 
305-243-4421 (ph)
305-243-3955 (fax)
Room 239 DB, R. Bunn Gautier Building
email 
Dorraya  El-Ashry, Ph.D. Dorraya El-Ashry, Ph.D.
Associate Professor of Internal Medicine
Research Summary
Mechanisms underlying the etiology of ER-negative vs ER-positive breast cancer and studies aimed at re-expressing ER in ER-negative tumors leading to clinical trials.
 
(305) 243-4721 (ph)
email 
Mohammad  Faghihi, M.D., Ph.D. Mohammad Faghihi, M.D., Ph.D.
Assistant Professor of Psychiatry & Behavioral Sciences, Neuroscience Program Affiliated Faculty Member
Research Summary
Dr. Faghihi's interests include non-protein-coding RNAs and their involvement in neurological disorders such as Alzheimer's disease, Parkinson's disease, Multiple Sclerosis and Fragile X Syndrome.
 
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305-243-7953 (ph)
Biomedical Research Building
email 
Christian  Faul, Ph.D. Christian Faul, Ph.D.
Assistant Professor of Medicine/Nephrology and Cell Biology
Research Summary
The Synaptopodin family of actin binding proteins and its role in signal transduction in renal podocytes and cardiac myocytes
 
(305)243-3206 (ph)
(305)243-3209 (fax)
Batchelor Bldg 6th Fl Room #628
email 
Alessia  Fornoni, MD, PhD Alessia Fornoni, MD, PhD
Assistant Professor
Research Summary
Research focuses on characterizing the molecular mechanism responsible for diabetic complications, mainly kidney disease.
 
305-243-3583 (ph)
305-243-4404 (fax)
DRI, 1450 NW 10th Ave, Room 5010
 
John R. Gilbert, Ph.D. John R. Gilbert, Ph.D.
Professor, Dr. John T. Macdonald Foundation Department of Human Genetics, Hussman Institute for Human Genomics.
Research Summary
Dr. Gilbert's research focuses on applications of genome technology to human genetics and the molecular genetics of autism, Alzheimer disease, Essential Tremor, and infectious disease such as tuberculosis. As a molecular biologist, his expertise is in gene analysis and characterization, positional cloning, mutation analysis, and animal models of human disorders.
 
305-243-6177 (ph)
305-243-2396 (fax)
Room 510, Biomedical Research Building
email 
Guy A. Howard, Ph.D.
Professor of Biochemistry & Molecular Biology
Research Summary
Cell and molecular biology of bone; cell and molecular biology of aging; stem cells and reparative medicine
 
Luca  Inverardi, M.D. Luca Inverardi, M.D.
Research Professor of Medicine, Deputy Director of Translational Research at the Diabetes Research Institute
305-243-5347 (ph)
305-243-4404 (fax)
Room 5006, Diabetes Research Institute
email 
Robert W. Keane, Ph.D. Robert W. Keane, Ph.D.
Professor, Physiology and Biophysics
Research Summary
"My research focuses on the initiation of inflammation, autophagy and apoptosis in the CNS after traumatic brain and spinal cord injury."
 
305-243-5726 (ph)
Rosenstiel Medical Science Building Room - 5058
email 
Richard  Lee, M.D., Ph.D. Richard Lee, M.D., Ph.D.
Associate Professor, Ophthalmology and Cell Biology
Research Summary
My lab studies molecular pathways important for retinal ganglion cell death and survival and the molecular pathophysiology of ocular disease
 
(305) 547-3686 (ph)
Bascom Palmer Eye Institute
email 
Jie  Li, M.D. Jie Li, M.D.
Associate Professor, Department of Dermatology and Cutaneous Surgery
Research Summary
Our laboratory uses advanced cell and molecular biology techniques and animal models to study skin related problems. We are specially interested in the function and mechanicsms involved in the epithelial extracellular matrix.
 
(305)243-3365 (ph)
(305)243-6191 (fax)
RMSB Rm 2049A
email 
Wei  Li, Ph.D. Wei Li, Ph.D.
Assistant Professor, Ophthalmology, Microbiology & Immunology, and Cell Biology
Research Summary
My research interests focus on two areas of eye diseases: autoimmune uveitis and retinal degeneration. For autoimmune uveitis, we investigate the mechanism of autoimmune uveitis by identifying and characterizing autoantigens directly from patients with non-invasive molecular biology approaches. For retinal degeneration, we investigate the role of retinal pigment epithelium (RPE) cell phagocytosis in retinal degeneration.
 
305-326-6445 (ph)
McKnight Vision Research Center - 619
email 
Marc  Lippman, M.D. Marc Lippman, M.D.
Kathleen and Stanley Glaser Professor of Medicine
Research Summary
molecular mechanisms of control of breast cancer growth and malignant behavior
 
(305) 243-9120 (ph)
(305) 243-9124 (fax)
email 
Balakrishna  Lokeshwar, Ph.D. Balakrishna Lokeshwar, Ph.D.
Professor/Co-Director Urology Research
Research Summary
"Functions of chemokines and pro-inflammatory factors in tumor progression, hormone-independence and metastasis. Development of natrually occuring compounds in herbs and spices for chemoprevention and therapy."
(305) 243-1012 (ph)
Gautier Medical Research Building, 1011 NW 15th Street
email 
Izidore  Lossos, M.D. Izidore Lossos, M.D.
Professor of Medicine and Director Lymphoma Program
Research Summary
We are studying pathogenesis of lymphoma and biological processes in normal B cells
 
305-243-6787 (ph)
305-243-4785 (fax)
Sylvester Comprehensive Cancer Center, D8-4
email 
Jaime  Merchan, M.D., MMSc Jaime Merchan, M.D., MMSc
Assistant Professor of Clinical Medicine
Research Summary
"My research interests include tumor angiogenesis, development of novel vascular targeted therapies for cancer, and identification of tumor and blood angiogenesis biomarkers that may serve as predictive or monitoring tools for cancer patients during treatment"
 
305-243-4909 (ph)
305-243-9161 (fax)
 
Enrique A. Mesri, Ph.D. Enrique A. Mesri, Ph.D.
Associate Professor of Microbiology and Immunology
Research Summary
"Molecular, cellular and genetic mechanisms of viral carcinogenesis of Kaposi sarcoma. Activation of tumor angiogenesis and genetic instability by the Kaposi sarcoma herpesvirus/ KSHV."
 
305-243-5659 (ph)
305-243-8309 (fax)
Room 109B (office), 134 (lab) Papanicolaou Cancer Research Building
email 
Carlos T. Moraes, Ph.D. Carlos T. Moraes, Ph.D.
Professor, Neurology and Cell Biology
Research Summary
Human Genetics; Molecular pathogenesis of disease-related mitochondrial DNA mutations
 
(305)243-5858 (ph)
(305)243-3914 (fax)
230 Two Story Lab
email 
Richard S. Myers, Ph.D. Richard S. Myers, Ph.D.
Lecturer, Department of Biochemistry & Molecular Biology
Research Summary

The mechanics of inheritance, DNA damage repair and its consequences, genome engineering using viral recombinases.

(305) 243-2056 (ph)
(305) 243-3065 (fax)
email 
Michael  Norenberg, M.D. Michael Norenberg, M.D.
Professor, Pathology
Research Summary
(305) 585-7049 (ph)
305-585-5311 (fax)
Holtz Center - JMH East Tower - 2412
email 
Savita  Pahwa, M.D. Savita Pahwa, M.D.
Professor of Microbiology and Immunology, Director of CFAR
Research Summary
Our group is interested in the immunopathogenesis of HIV infection for the understanding of the nature and mechanisms of immune dysfunction in HIV infected pediatric and adult patients. We hope that our studies will help in developing strategies for immune reconstitution, and for aborting disease progression in HIV infected subjects.
 
305-243-7732 (ph)
305-243-7211 (fax)
Room 712 (office), 708 (lab) Batchelor Children's Research Institute
email 
Justin M. Percival, Ph.D. Justin M. Percival, Ph.D.
Assistant Professor of Molecular and Cellular Pharmacology
Research Summary

We study the function of nitric oxide-cGMP signaling pathways in normal and diseased skeletal and cardiac muscle.  We use our findings to develop pharmacological treatments for muscle dysfunction in human disease.

305-243-7303 (ph)
305-243-4555 (fax)
RMSB 6174
email 
Jochen  Reiser, M.D., Ph.D. Jochen Reiser, M.D., Ph.D.
Professor of Medicine, Cell Biology; Chief, Div of Nephrology and Hypertension; Director, Peggy and Harold Katz Family Miami Drug Discovery Center
Research Summary
Cell Biology of podocytes and glomerular disease
 
305-585-1111 (ph)
email 
Joseph D. Rosenblatt, M.D. Joseph D. Rosenblatt, M.D.
William Harrington Professor of Medicine, Microbiology and Immunology and Chief of the Division of Hematology/Oncology
Research Summary
"Research into human gene therapy, anti-angiogenic and immune therapy applications for cancer including the design of novel antibody fusion proteins"
 
305-243-4860 (ph)
305-243-9161 (fax)
 
Richard L. Rotundo, Ph.D. Richard L. Rotundo, Ph.D.
Professor of Cell Biology, Physiology and Biophysics, and Member, Neurosciences Program
Research Summary
Membrane protein biogensis and localization; signal transduction; gene expression and regulation; nerves and muscle
 
(305)243-6940 (ph)
(305)545-7166 (fax)
Rosenstiel Medical Science Building - 4168
email 
Pedro  Salas, M.D., Ph.D. Pedro Salas, M.D., Ph.D.
Professor, Cell Biology
Research Summary
Polarization in epithelial cells; Role of the cytoskeleton and signaling pathways
 
305-243-6977 (ph)
Rosenstiel Medical Sciences Building 4090
email 
Matthias A Salathe, M.D. Matthias A Salathe, M.D.
Chief, Division of Pulmonary & Critical Care, and Professor of Medicine and Molecular & Cellular Pharmacology
Research Summary
"Research focuses on innate host defenses of the airways including mucociliary clearance, mucus secretion, ciliary beating and lactoperoxidase system and recovery from insults."
 
305-585-7340 (ph)
305-243-6992 (fax)
Rosenstiel Medical Sciences Building, 7063A
email 
Paul  Schiller, Ph.D. Paul Schiller, Ph.D.
Research Associate Professor of Medicine
Research Summary
"Marrow-isolated adult mutilineage inducible (MIAMI) stem cells: molecular mechanisms of self-renewal, proliferation and differentiation; and their use in regenerative medicine."
 
Stephan C.  Schurer, Ph.D. Stephan C. Schurer, Ph.D.
Research Assistant Professor, Molecular & Cellular Pharmacology, Adjunct Assistant Professor, Molecular Therapeutics, The Scripps Research Institute Florida
Research Summary
Computer-Aided Drug Design, semantic integration, cheminformatics, computational poly-pharmacology
 
305-243-4842 (ph)
305-243-4555 (fax)
CRB 944
email 
Jose P. Silva, MD, Ph.D. Jose P. Silva, MD, Ph.D.
Research Assistant Professor
Research Summary
Dr. Silva is interested in studying the central and peripheral mechanisms that control energy and glucose balance, the role of non-protein coding RNAs in metabolic gene regulation and strategies to target non-protein coding RNAs as drug therapies for obesity, diabetes and cardiovascular disease.
 
305-243-1209 (ph)
305-243-2396 (fax)
Room 433, Biomedical Research Building
email 
Rakesh  Singal, M.D. Rakesh Singal, M.D.
Associate Professor of Medicine/Hematology/Oncology
Research Summary
Dr. Singal’s research focuses on the epigenetic mechanisms that inactivate certain tumor-suppressor genes in prostate cancer and designing clinical trials based on lab research.
 
305-243-4909 (ph)
305-243-4905 (fax)
Sylvester Comprehensive Cancer Center
email 
Joyce M. Slingerland, MD, PhD Joyce M. Slingerland, MD, PhD
Director, Braman Family Breast Cancer Institute, UMSylvester Comprehensive Cancer Center Professor of Medicine
Research Summary
Breast cancer, molecular mechanisms, molecular genetics, epidemiology, cell cycle, and estrogen receptors
 
305-243-4909 (ph)
305-243-4975 (fax)
email 
Michal  Toborek, M.D., Ph.D. Michal Toborek, M.D., Ph.D.
Professor and Vice Chair for Research
Research Summary
Studies on the integrity of the blood-brain barrier (BBB)
and how different pathological conditions can lead to the
disruption and/or dysfunction of the BBB.
305-243-0230 (ph)
305-243-3955 (fax)
Room 516, R. Bunn Gautier Building (Locator R-629)
email 
Kathryn W. Tosney, Ph.D. Kathryn W. Tosney, Ph.D.
Chair, Biology
Research Summary
The Tosney lab studies axon guidance and growth cone motility.
 
(305) 284-4134 (ph)
Cox Science Center - 215
email 
Claes  R.  Wahlestedt, M.D, Ph.D. Claes R. Wahlestedt, M.D, Ph.D.
Director, Genomic Interdisciplinary Therapeutic Innovation Center (G-ITIC)
Research Summary
Dr. Wahlestedt's research interests focus on novel drug therapies for neuropsychiatric disorders and epigenetics.
 
305-243-7694 (ph)
305-243-2396 (fax)
Room 407, Biomedical Research Building
email 
Keith  Webster, Ph.D. Keith Webster, Ph.D.
Professor of Molecular and Cellular Pharmacology; Director of the Vascular Biology Institute; Walter G. Ross Chair of Vascular Biology
Research Summary
Myocardial ischemia, Apoptosis, Gene and Stem Cell Therapy  
 
305-243-6779 (ph)
305-243-6082 (fax)
Rosenstiel Medical Sciences Building 6038
email 
Rong  Wen, M.D., Ph.D. Rong Wen, M.D., Ph.D.
Professor, Opthamology
Research Summary
Retinal cell biology; photoreceptor degeneration; retinal vascular disorders
 
(305) 482-4874 (ph)
McKnight Vision Research Center - 506
email 
 
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